Introduction
Most of the tannins which are condensed besides those which are hydrolyzable are soluble in water. In introduction, in the context of best OPC or oligomeric proanthocyandin in connection with OPC, OPC 3, and OPC 3 supplement and for which one may even visit links like http://stores.opc-antioxidant.com, it is also quite important to know that some of those tannins which are condensed may not be soluble besides several others may be highly soluble in octanol, which is an organic compound having a particular and specific molecular formula. The aforementioned may come in the category of those acids which are fatty. Results of experiments have proven that procyanidins serve the purpose of modulators in the response of immune in macrophages. However, for the effects of health, one needs to study those controlled trials which are randomized for the assessment of whether its benefits, as is claimed, have the support of any evidence or not. Reviews of such trials, conducted earlier, are not sufficient to corroborate remedial values of Pycnogenol.
Evaluation
Though there is no industry standard for the accurate identification and quantification of oligomeric proanthocyandins, most products which come in the aforementioned category contain those extracts which are untraceable besides being unidentifiable and which can vaguely be labeled as extracts of pine bark or grape seeds. In evaluation of safe OPC nutrition products, one must also know that researchers have still remained unable to find the origins of those ingredients which are used in the production of oligomeric proanthocyandins besides its method.
Information pertaining to the place where the extract had first been manufactured besides the local standards with which it had been produced is yet to be found out. Some of those products which come in the category of oligomeric proanthocyandins comprise only grape seeds or parts of other plants the pulverization of which has been done in processors of food, since extract production is less expensive in comparison to isolating oligomeric proanthocyandines. Many manufacturers make the use of chemical solvents which are very different from the ethanol extracts.
Safety
Bioflavonoids, which may be defined as a particular type of flavonoids and the category of which may be extremely varied and complex, are quite mutagenics with the result that those extracts which have not been tested may pose danger to one’s health. In safety, in the context of grape seed extract, it is also extremely important to know that those flavonoids which have been highly defined are considered to be extremely safe. Some very strict guidelines, in the context of health, have been set forth and according to which, such extracts need to undergo intensive analytical, pharmacological, toxicological, and biological research before they may be registered as medicines. In many countries, rigorous testing of the standards of such supplements is considered to be extremely important and without which the aforementioned would not be declared safe for general consumption.
There are absolutely no analytical traces or evidence, which may be clear besides being accepted commonly, for the qualification of the extract of grape seeds. A French doctor originally invented such extracts.
Organic Structure
Unlike those nutrients which are single and some examples of which would include Alphatocopherol which can be categorized as vitamin E and ascorbic acid which is a type of vitamin C, oligomeric proanthocyandines are too complex besides requiring technology and knowledge which has to be very specialized. In organic structure, on the topic of pine bark extract, one must gain information about the organic clusters which may be inclusive of two dimers, three trimers, four tetramers, and five pentamers, and not being any larger. Those epicatechins and catechins which are single act very differently from all those ones which may be bonded as oligomeric proanthocyandines. Several patents were received for isolating and extracting the aforementioned commercially from grape seeds and the bark of pine. Such complexes, which are highly defined ones, may be subject to very intensive analytic, pharmacological, toxicological, and biological research. Many consumers of natural foods besides retailers of the aforementioned consider extracts of grape seeds to be untraceable and unidentifiable materials being unrelated to the scientific methods.
Isolation
For being effective, clusters of proanthocyanidines must have one particular molecular size. In isolation of polymeric proanthocyanidines from oligomeric while discussing the best OPC or oligomeric proanthocyandin in connection with OPC, OPC 3, and OPC 3 supplement, it would be appropriate to mention here that due to its molecular size, the supplement mentioned above cannot pass that tract which is intestinal, and into the stream of blood and due to which, it can be described as nonnutritive. Due to their size, tannins cannot fit between the collagen fibrils besides being unable to repair the collagen which is decayed. Though tennins have an affinity towards proteins like the oligomeric proanthocyanidines, the magnitude taken by the aforemetioned may not be healthy at all due to their size which is on the larger side. The power of tennins can be estimated by the fact that they rush where the oligomeric proanthocyandines remain in check with those tissues which are protected by them and which are extremely delicate. Tennins are used for leather tanning.
